Subject headings: microwave; analgesics; pain, intractability

Abstract: Non-opioids have less side effects in the treatment of cancer pain, but their analgesic effects are weak, and have little effect on patients with severe cancer pain. Opioids have strong analgesic effects and have greater side effects. Repeated use can cause physical dependence and addiction. Sex, large doses cause respiratory depression and cause coma. Therefore, in the clinical treatment of cancer patients, the contradiction of "pain and control" often occurs. In order to explore other effective methods to resolve this contradiction, millimeter waves are used to assist cancer pain.

1. Materials and methods

1.1 Materials 2002 05 01 ~ 07 01 Undergraduate hospitalized patients were clinically and pathologically diagnosed as malignant tumors and 57 cases of pain of grade II and III, 33 males and 24 females. Age from 18 to 85 years old, average 52 years old. There were 17 lung cancers, 13 stomach cancers, 8 breast cancers, 4 liver cancers, 5 rectal cancers, 7 esophageal cancers, and 3 malignant lymphomas. Pain is graded according to the WHO pain grading standard (1), grade I (mild pain), there is pain, but can be tolerated, and can live a normal life, sleep is not disturbed; grade II (moderate pain), the pain is obvious, unbearable, need to take Pain relievers relieve symptoms, sleep is disturbed; Grade III (severe pain), the pain is severe and unbearable, need to take strong analgesics to relieve symptoms, sleep is seriously disturbed. The cases in this group are all grade Ⅱ and Ⅲ.

1.2 Method Randomly draw lots and divide them into two groups, 31 cases in the treatment group and 26 cases in the control group. The treatment group was treated with acupoints with millimeter wave therapeutic apparatus based on the application of analgesics according to the WHO analgesic plan. The main points and matching points are combined. Place the millimeter-wave four-radiation probe on the skin surface of the main acupoint and the matching acupoint respectively, and fix it, and turn on the power switch. 1 time/d, 30min/time, 10 times is a course of treatment, and the curative effect is judged after the end of 3 courses. The control group was treated with only analgesics at the same time as the WHO analgesic plan, and the same analgesics used in the treatment group for patients with the same level of pain. First start with non-opioid preparations, indomethacin 75mg, 3 times/d orally, if ineffective, change to Bucinzine tablets 100mg, 3 times d po, ​​if severe pain cannot be relieved, change to morphine 10mg, 2 times/d im, Later, as the degree of pain worsened, gradually increase the daily dose of morphine.

1.3 The data obtained by statistical processing is tested with X2.

2 results

2.1 The efficacy is judged to be effective: the analgesic is reduced or downgraded, and the pain is relieved; the analgesic remains unchanged and the pain is not aggravated. Ineffective: Pain relievers increase or escalate, and pain gradually worsens.

2.2 Evaluation results Comparison of the pain levels of the two groups before treatment, the treatment group has 15 cases of grade II, 16 cases of grade III, 12 cases of grade II pain in the control group, and 14 cases of grade III pain. Statistical analysis x2=0.028 P>0.05, the difference was not significant. Comparison of the effects of pain treatment between the two groups of patients, the treatment group was effective in 25 cases and ineffective in 6 cases, the total effective rate was 80.6%, and the control group was effective in 11 cases and ineffective in 15 cases, the total effective rate was 42.3%, statistical processing x2=8.09P>0.005 The difference is not significant.

3 Discussion

The principle of 　　 millimeter wave treatment instrument is to use energy resonance to stimulate the metabolism of the human body through the generated energy. After the wave radiates acupuncture points, the local resonance effect is generated and the acupoints are stimulated to produce biological effects. Studies have shown that A millimeter waves can dilate capillaries and change blood flow speed, thereby improving local tissue perfusion, enhancing tissue and cell nutrition metabolism, and improving tissue and cell function and regeneration, thereby promoting inflammation absorption, swelling elimination, and spasm relief . Studies have also shown that millimeter waves have unique non-biological and long-distance effects. They stimulate menstrual qi through acupoints, regulate the patient’s endocrine, activate the pain modulation system in the body, strengthen local metabolism, and accelerate the excretion of local pain-causing substances, thereby alleviating pain. In addition, there are data to prove (2): Millimeter wave has a significant inhibitory and killing effect on cancer cells, so that the cancer is continuously suppressed and the pain gradually disappears, which is not available in any painkiller.

This study found that: of the effective 25 cases in the treatment group, 19 cases of painkillers were downgraded or reduced, and pain was relieved. Only 6 cases of painkillers remained unchanged and pain did not worsen. In the 11 cases in the control group, the painkillers remained unchanged, and the pain did not worsen. Millimeter wave treatment is significantly reduced

It reduces the degree of cancer pain in patients, thus greatly reducing the dosage or intensity of analgesics used by patients, reducing the harm of body dependence, addiction, and respiratory depression caused by drugs, and reducing the contradiction between "pain and control" . At the same time, the treatment method is simple, no damage, no toxic side effects, and patients are willing to accept it.

4 References (omitted)