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Observation of the Efficacy of Millimeter Wave Therapy for Soft Tissue Injuries in the Neck and Shoulder Region

A total of 48 patients with soft tissue injuries in the neck and shoulder region due to millimeter-wave therapy were enrolled, including 19 males and 29 females; their ages ranged from 31 to 81 years, with disease durations spanning from 2 days to 1 year. Among them, 25 cases presented with soft tissue injuries of the neck, while 23 cases involved soft tissue injuries of the shoulder. All patients were treated using a millimeter-wave therapeutic device with an output power of 80 mW, an oscillation frequency of 37.5 GHz, and a wavelength of 8 mm. The device delivered square-wave pulsed output, with low-frequency modulation ranging from 1 to 100 Hz and a pulse duty cycle between 10% and 100%. The radiation head was cylindrical, with a diameter of 6 cm. The intensity setting was adjusted to 6–8, corresponding to a duty cycle of 60%–80%; the wave number setting was set to 6–8, resulting in a pulse modulation frequency of 2.4–5.0 Hz. The patient’s treatment position was determined based on their specific condition, with the radiation head positioned perpendicular to the target area for direct irradiation. Each session lasted 20 minutes, with treatments administered once daily or every other day, totaling 6–12 sessions per course of therapy. The control group received traditional massage techniques, with each session lasting 20 minutes, administered once daily or every other day, also comprising 6–12 sessions per course of therapy. Efficacy Criteria: Complete Remission—All symptoms and signs disappeared, and function returned to normal; Marked Improvement—Significant improvement in symptoms and signs compared to baseline; Improvement—Moderate improvement in symptoms and signs compared to baseline; No Effect—No change in symptoms or signs compared to baseline. The millimeter-wave group underwent 3–12 treatment sessions, averaging 7.8 sessions. Among them, 20 cases achieved complete remission, accounting for 41.7%; 17 cases showed marked improvement, representing 35.4%; 9 cases were effective, constituting 18.8%; and 2 cases were deemed ineffective, making up 4.1%, often in conjunction with manual therapy. The overall efficacy rate was 96%, with 77.1% achieving marked improvement or better (see Appendix). In the control group, 8 cases achieved complete remission, accounting for 16.7%; 17 cases showed marked improvement, representing 35.4%; 19 cases were effective, accounting for 39.6%; and 4 cases were deemed ineffective, comprising 8.3%. The difference in the proportion of patients achieving marked improvement or better between the two groups was statistically significant (P < 0.05), indicating that the millimeter-wave treatment group demonstrated superior therapeutic efficacy compared to the control group.

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341

10

2023-05

The Effects of Millimeter Wave Therapy on Respiratory Diseases

In recent years, advancements in millimeter-wave technology have been steadily applied to the field of biomedicine. Through extensive experimentation, scientists have discovered that millimeter waves possess unique biological significance: millimeter-wave irradiation exerts profound effects on living organisms and holds considerable clinical value. Principle: Millimeter-wave therapy refers to a novel therapeutic approach in which low-power (low-intensity) ultra-high-frequency electromagnetic waves induce resonance with living cells and molecules. These waves are then transmitted and amplified through the body’s meridian, nervous, endocrine, and immune systems—key biological functional networks—ultimately reaching the target sites to exert therapeutic effects, thereby promoting disease prevention and health enhancement. Mechanism of Action: At its core, millimeter-wave therapy involves information regulation at the cellular and molecular levels. It can effectively improve and correct physiological functions, modulate the body’s immune response and overall resistance, and maintain and restore physiological homeostasis. Clinically, it is used to alleviate respiratory symptoms, relieve spasm and suppress cough, reduce inflammation and relieve pain, and accelerate the absorption of pulmonary and tracheal inflammation. 1. Millimeter-wave radiation non‑specifically activates immune system cells, increasing their activity and enhancing both cellular and humoral immune responses. It improves T‑cell–mediated immune reactions and strengthens the body’s overall resistance. 2. Millimeter-wave radiation promotes vasodilation in the lungs and accelerates microcirculation, boosting the activity of macrophages and phagocytic cells. This process speeds up the absorption and elimination of pathological and metabolic byproducts, thereby accelerating the repair of pulmonary edema and inflammation. 3. Millimeter-wave radiation enhances nutrition and metabolism within lung tissue, improving its function and regenerative capacity while accelerating the repair of tissues and organs. 4. When combined with pharmacological treatment, millimeter waves can enhance drug absorption and reduce the toxic side effects of medications. Clinical Applications: Adjunctive treatment for conditions such as pneumonia, bronchitis, gastroenteritis, and diarrhea. Advantages: 1. Millimeter waves are classified as a non‑thermal therapy; the treatment process is free from consumables, pollution, and radiation. 2. Millimeter-wave therapy exhibits a cumulative effect over time—after treatment is discontinued, its beneficial effects continue for a sustained period. 3. Treatment is administered via affected areas or acupoints, with energy transmitted along the meridians, amplifying the therapeutic outcome. Methods: For Pneumonia: Lung Shu Point, Tian Tu Point, and Dan Zhong Point; For Diarrhea: Zhong Wan Point, Shang Wan Point, and Tian Shu; To Boost Immunity: Hegu Point, Zusanli Point, and Neiguan Point.

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480

04

2023-01

Analysis of 100 Cases Treated with Microwave Ablation for Digestive Tract Diseases

In recent years, we have employed microwave technology to treat 100 cases of gastrointestinal disorders via endoscopy, including 57 cases of polyps (57.0%), 20 cases of gastric mucosal prolapse (20.0%), 14 cases of verrucous gastritis (14.0%), and 9 cases of advanced tumors (9.0%). The therapeutic outcomes have been remarkable, as detailed below. Materials and Methods 1.1 Clinical Data: A total of 100 patients were included, comprising 76 males and 24 females, with an average age of 52 years. Symptoms varied widely, including upper abdominal fullness and distension, belching, abdominal pain, acid reflux, dysphagia, diarrhea, melena, or hematochezia. Endoscopic findings revealed: 57 cases of polyps (57.0%)—including 19 gastric polyps and 38 colonic polyps, totaling 79 lesions—of which 26.6% were broad-based polyps, 51.9% were semi‑broad-based polyps, 19.0% had long stalks, 2.5% were filiform polyps, and 15 polyps exceeded 1 cm in diameter. Twenty cases (20%) exhibited gastric mucosal prolapse, 14 cases (14.0%) were diagnosed with verrucous gastritis, and 9 cases (9.0%) were advanced tumors—specifically, 7 cases of esophageal cancer and 2 cases of colon cancer. Pathological analysis showed: ① Polyps: 78.9% were inflammatory, 19.3% were adenomatous, and 1.8% were juvenile; ② Gastric mucosal prolapse: 70.0% presented as superficial inflammation, while 30.0% showed atrophic inflammation; ③ Verrucous gastritis: 57.1% displayed atrophic inflammation, and 28.6% exhibited atrophic inflammation accompanied by intestinal metaplasia or dysplasia; ④ Tumors: 55.6% were squamous cell carcinoma of the esophagus, and 44.4% were adenocarcinoma of the colon. 1.2 Instruments and Methods: Microwave therapy device. Procedure: Prior to treatment, patients received a routine intramuscular injection of 654-2 at 10 mg. Output power was adjusted according to lesion size and morphology, typically ranging from 40 to 60 W. A spherical antenna was inserted through the biopsy channel to precisely target and contact the lesion. Depending on the lesion’s shape, either a “top‑pressure” “ironing” technique was employed, or a “cutting” approach was applied along both sides of the neck. Foot pedal control regulated the duration of thermal ablation, generally lasting 10–30 seconds, until the tissue coagulated to a whitish appearance or became carbonized. For polyps larger than 1 cm and for cases of gastric mucosal prolapse, 3–8 ml of 3.3% hypertonic saline containing norepinephrine was injected submucosally at multiple points along the base of the polyp and the margins of the prolapsed mucosa, inducing localized swelling and mucosal elevation. Subsequent microwave thermocoagulation effectively prevented or reduced bleeding and helped to avoid perforation of the digestive wall. For verrucous gastritis, papular elevations were smoothed out; within 3 days after treatment, patients were placed on a semi‑liquid diet and routinely administered H2‑receptor antagonists or proton pump inhibitors, supplemented with mucosal protectants for 1–4 weeks. Following treatment for colonic disease, patients were prescribed oral fleroxacin for 1 week. All cases underwent follow‑up endoscopy within 2–8 weeks. 1.3 Efficacy Assessment Healing (effective): Polyps completely disappeared, gastric mucosal prolapse resolved or decreased by more than 50%, papular elevations of the gastric mucosa vanished, and associated symptoms were alleviated or significantly reduced. In patients with esophageal or colon cancer, obstruction symptoms improved, and food intake increased compared to pre‑treatment levels. Ineffective: Cases that failed to meet the above criteria. 1.4 Results: All 57 polyps (totaling 79 lesions) were completely eradicated, yielding a 100% cure rate. Among the 20 cases of gastric mucosal prolapse, 12 cases saw complete resolution of the prolapsed gastric mucosa, while 7 cases experienced a reduction of over 50%, with accompanying relief or disappearance of upper abdominal pain—a 95.0% cure rate, with 1 case (5.0%) deemed ineffective. Of the 14 cases of verrucous gastritis, papular elevations disappeared entirely, and symptoms improved markedly, resulting in a 100% cure rate. Among the 9 cases of advanced tumors, 7 cases (77.8%) showed effective responses, while 2 cases (22.2%) were deemed ineffective; one of the latter cases developed complications. 2. Discussion Microwave therapy has demonstrated a one‑time cure rate exceeding 90% for gastrointestinal polyps, with no serious adverse events reported. This technique has since been extended to applications such as the management of gastrointestinal bleeding and tumor ablation. In our series of 57 cases (79 polyps), all lesions were completely eliminated following microwave thermocoagulation, achieving a 100% cure rate. While high‑frequency electrocautery and wet microwave coagulation are commonly used to treat large polyps, these methods often carry a higher risk of intra‑ and postoperative bleeding or perforation. To address this, we first injected hypertonic saline containing norepinephrine submucosally at the base of large polyps and along the margins of prolapsed mucosa, then proceeded with microwave thermocoagulation. The mechanisms underlying this approach are as follows: Hypertonic saline induces tissue swelling and causes denaturation of vascular fibrin, leading to vasoconstriction, occlusion, and thrombus formation. Norepinephrine further constricts blood vessels, while the locally hypertonic environment prolongs the pharmacological effects of norepinephrine, thereby disrupting the blood supply to the polyp and causing it to shrink. This dual action not only provides prophylactic hemostasis but also shortens the duration of thermal ablation. Moreover, injecting hypertonic saline containing norepinephrine submucosally at the base of the polyp increases the distance between the mucosa and the muscular layer, reducing the depth of thermal injury inflicted by the microwave on the gastrointestinal wall and effectively preventing perforation of the digestive tract. Verrucous gastritis is a distinct subtype of gastritis. By using microwave therapy to smooth out papular lesions, followed by administration of acid‑suppressing agents, we achieved high therapeutic efficacy with a 100% cure rate. Microwave thermocoagulation of elevated malignant lesions in the gastrointestinal tract can reduce tumor size, alleviate obstructive symptoms, and improve the quality of life for cancer patients. Microwave therapy for gastrointestinal diseases offers reliable efficacy, high safety, and relatively low equipment costs, making it well suited for widespread adoption across various hospitals.

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463

11

2022-05

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